Quantitative monitoring of omeprazole synthesis reaction and crystallization by in-line Raman spectroscopy
The development of a quantitative in-line Raman spectroscopic method for in situ monitoring
of the active pharmaceutical ingredient, omeprazole synthesis reaction and crystallization is
described. In-line monitoring was performed using a dispersive Raman instrument. Prior to
reaction monitoring, the reaction components were characterized off-line by means of Raman
and NMR spectroscopy. The spe…
Rannchuiditheoirí
- Novak, Predrag
Cruthaitheoir
- Šahnić, Damir
Foilsitheoir
- University of Zagreb. Faculty of Science. Department of Chemistry.
Ábhar
- in-line Raman spectroscopy
- in situ quantitative monitoring
- multivariate calibration
- omeprazole
- NATURAL SCIENCES. Chemistry.
- Chemistry. Crystallography. Mineralogy
Cineál míre
- info:eu-repo/semantics/doctoralThesis
- text
Dáta
- 2017-09-18
- info:eu-repo/date/embargoEnd/2019-09-18
- 2017-09-18
Rannchuiditheoirí
- Novak, Predrag
Cruthaitheoir
- Šahnić, Damir
Foilsitheoir
- University of Zagreb. Faculty of Science. Department of Chemistry.
Ábhar
- in-line Raman spectroscopy
- in situ quantitative monitoring
- multivariate calibration
- omeprazole
- NATURAL SCIENCES. Chemistry.
- Chemistry. Crystallography. Mineralogy
Cineál míre
- info:eu-repo/semantics/doctoralThesis
- text
Dáta
- 2017-09-18
- info:eu-repo/date/embargoEnd/2019-09-18
- 2017-09-18
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Aitheantóir
- https://dr.nsk.hr/islandora/object/pmf:2040
- https://urn.nsk.hr/urn:nbn:hr:217:702684
- https://repozitorij.unizg.hr/islandora/object/pmf:2040
- https://dr.nsk.hr/islandora/object/pmf%3A2040/datastream/TN/view/
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- application/pdf
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