Mechanisms by which the p53 tumor suppressor mediates pathological manifestations in Rpl24-heterozygous mice
Title: Mechanisms by which the p53 tumor suppressor mediates pathological manifestations in Rpl24-heterozygous mice
Objectives:
Upregulation of p53 and Sesn2 in Rpl24-heterozygous mice suggests that p53 regulates pathological manifestations of these mice through Sesn2-dependent regulation of autophagy and mTOR signalling pathway.
Our objectives are:
1. To determine if p53-dependent induction…
Kontributuri
- Volarević, Siniša
Kreatur
- Cokarić Brdovčak, Maja
Pubblikatur
- University of Rijeka. Faculty of Medicine.
Suġġett
- BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences.
- Pathology. Clinical medicine
- Autophagy
- p53-dependent checkpoint mechanism
- ribosomes
- ribosomal protein L24
- Rpl24-heterozygous mice
Tip ta' oġġett
- info:eu-repo/semantics/doctoralThesis
- text
Data
- 2014-01-01
- 2014-01-01
Kontributuri
- Volarević, Siniša
Kreatur
- Cokarić Brdovčak, Maja
Pubblikatur
- University of Rijeka. Faculty of Medicine.
Suġġett
- BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences.
- Pathology. Clinical medicine
- Autophagy
- p53-dependent checkpoint mechanism
- ribosomes
- ribosomal protein L24
- Rpl24-heterozygous mice
Tip ta' oġġett
- info:eu-repo/semantics/doctoralThesis
- text
Data
- 2014-01-01
- 2014-01-01
Istituzzjoni fornitriċi
Aggregatur
Dikjarazzjoni tad-drittijiet tal-midja f'dan ir-rekord (sakemm mhux speċifikat mod ieħor)
- http://rightsstatements.org/vocab/InC/1.0/
Identifikatur
- https://dr.nsk.hr/islandora/object/svkri:2861
- https://urn.nsk.hr/urn:nbn:hr:188:341253
- https://www.unirepository.svkri.uniri.hr/islandora/object/svkri:2861
- https://dr.nsk.hr/islandora/object/svkri%3A2861/datastream/TN/view/
Format
- application/pdf
Lingwa
- hrv
Pajjiż fornitur
- Croatia
Isem il-kollezzjoni
L-ewwel darba ppubblikata fuq Europeana
- 2019-04-05T13:44:13.476Z
L-aħħar aġġornament mill-istituzzjoni fornitriċi
- 2019-04-05T13:44:13.476Z